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AN INTRODUCTORY TEXT TO BIOENGINEERING 2008 (P)
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ISBN: 9789812707949
類別: 生物科學Biophysics Science
出版社: WORLD SCIENTIFIC PUBLISHING CO
作者: CHIEN
年份: 2008
裝訂別: 平裝
頁數: 540
定價: 1,100
售價: 990
原幣價: USD 55.00
狀態: 正常
This bestselling textbook will introduce undergraduate bioengineering students to the fundamental concepts and techniques, with the basic theme of integrative bioengineering. It covers bioengineering of several body systems, organs, tissues, and cells, integrating physiology at these levels with engineering concepts and approaches; novel developments in tissue engineering, regenerative medicine, nanoscience and nanotechnology; state-of-the-art knowledge in systems biology and bioinformatics; and socio-economic aspects of bioengineering.

One of the distinctive features of the book is that it is integrative in nature (integration of biology, medicine and engineering, across different levels of the biological hierarchy, and basic knowledge with applications). It is unique in that it covers fundamental aspects of bioengineering, cutting-edge frontiers, and practical applications, as well as perspectives of bioengineering development. Furthermore, it covers important socio-economical aspects of bioengineering such as ethics and entrepreneurism.

Contents:

*Perspectives of Biomechanics (Y-C B Fung & W Huang)

*Cardiac Electromechanics in the Healthy Heart (R C P Kerckhoffs & A D McCulloch)

*Cardiac Biomechanics and Disease (J H Omens)

*Bioengineering Solution for the Treatment of Heart Failure (J T Watson & S Chien)

*Molecular Basis of Modulation of Vascular Functions by Mechanical Forces (S Chien)

*Autoregulation of Blood Flow: Examining the Process of Scientific Discovery (P C Johnson)

*Molecular Basis of Cell and Membrane Mechanics (L A Sung)

*Cell Activation in the Circulation: The Auto-Digestion Hypothesis (G W Schmid-Sch霵bein)

*Blood Substitutes and the Design of Oxygen Non-Carrying and Carrying Fluids (M Intaglietta)

*Analysis of Human Pulmonary Circulation: A Bioengineering Approach (W Huang et al.)

*Pulmonary Gas Exchange (P D Wagner)

*Engineering Approaches to Understanding the Kidney (S C Thomson)

*Skeletal Muscle Tissue Bioengineering (R L Lieber & S R Ward)

*Multi-Scale Biomechanics of Articular Cartilage (W C Bae & R L Sah)

*Design and Development of an In Vivo Force-Sensing Knee Prosthesis (D D DLima & P C Y Chen)

*The Implantable Glucose Sensor in Diabetes: A Bioengineering Case Study (D A Gough)

*Stem Cells in Regenerative Medicine (S Chien & L S B Goldstein)

*Engineering Compounds Targeted to Vascular Zip Codes (E Ruoslahti)

*The Structure of the Central Nervous System and Nanoengineering Approaches for Studying and Repairing It (G A Silva)

*Cellular Biophotonics: Laser Scissors (Ablation) (M W Berns)

*Microelectronic Arrays: Applications from DNA Hybridization Diagnostics to Directed Self-Assembly Nanofabrication (M J Heller & D Dehlinger)

*Systems Biology: A Four-Step Process (J L Reed & B O Palsson)

*Bioinformatics and Systems Biology: Obtaining the Design Principles of Living Systems (S Subramaniam)

*Synthetic Biology: Bioengineering at the Genomic Level (N Ostroff et al.)

*Network Genomics (T Ideker)

*Genomes, Genomic Technologies and Medicine (X Huang)

*Ethics for Bioengineers (M Kalichman)

*Opportunities and Challenges in Bioengineering Entrepreneurship (J-S Lee)

*How to Move Medical Devices from Bench to Bedside (P Citron)

Table Of Contents

Contributors ix

Preface xvii

Acknowledgments xix

SECTION I: INTRODUCTORY CHAPTERS

Chapter 1: Overview 3
Shu Chien

Chapter 2: Perspectives of Biomechanics 13
Yuan-Cheng B. Fung and Wei Huang

SECTION II: CARDIOVASCULAR BIOENGINEERING

Chapter 3: Cardiac Electromechanics in the Healthy Heart 37
Roy C. P. Kerckhoffs and Andrew D. McCulloch

Chapter 4: Cardiac Biomechanics and Disease 53
Jeffrey H. Omens

Chapter 5: Bioengineering Solutions for the Treatment of Heart Failure 69
John T. Watson and Shu Chien

Chapter 6: Molecular Basis of Modulation of Vascular Functions by 79
Mechanical Forces
Shu Chien

Chapter 7: Autoregulation of Blood Flow: Examining the Process of 99
Scientific Discovery
Paul C. Johnson

SECTION III: BLOOD CELL BIOENGINEERING

Chapter 8: Molecular Basis of Cell and Membrane Mechanics 117
Lanping Amy Sung

Chapter 9: Cell Activation in the Circulation: The Auto-Digestion 131
Hypothesis
Geert W. Schmid-Schonbein
v

Chapter 10: Blood Substitutes and the Design of Oxygen Non-Carrying 149
and Carrying Fluids
Marcos Intaglietta

SECTION IV: RESPIRATORY-RENAL BIOENGINEERING

Chapter 11: Analysis of Human Pulmonary Circulation: 163
A Bioengineering Approach
Wei Huang, Michael R. T. Yen and Qinlian Zhou

Chapter 12: Pulmonary Gas Exchange 181
Peter D. Wagner

Chapter 13: Engineering Approaches to Understanding the Kidney 209
Scott C. Thomson

SECTION V: TISSUE ENGINEERING AND REGENERATIVE
MEDICINE

Chapter 14: Skeletal Muscle Tissue Bioengineering 225
Richard L. Lieber and Samuel R. Ward

Chapter 15: Multi-Scale Biomechanics of Articular Cartilage 243
Won C. Bae and Robert L. Sah

Chapter 16: Design and Development of an In Vivo Force-Sensing 261
Knee Prosthesis
Darryl D. D’Lima and Peter C. Y. Chen

Chapter 17: The Implantable Glucose Sensor in Diabetes: 279
A Bioengineering Case Study
David A. Gough
Chapter 18: Stem Cells in Regenerative Medicine 291
Shu Chien and Lawrence S. B. Goldstein

SECTION VI: NANOSCIENCE AND NANOTECHNOLOGY

Chapter 19: Engineering Compounds Targeted to Vascular 313
Zip Codes
Erkki Ruoslahti
vi Contents

Chapter 20: The Structure of the Central Nervous System and 327
Nanoengineering Approaches for Studying and
Repairing It
Gabriel A. Silva

Chapter 21: Cellular Biophotonics: Laser Scissors (Ablation) 353
Michael W. Berns

Chapter 22: Microelectronic Arrays: Applications from DNA Hybridization 369
Diagnostics to Directed Self-Assembly Nanofabrication
Michael J. Heller and Dietrich Dehlinger

SECTION VII: GENOMIC ENGINEERING AND SYSTEMS BIOLOGY

Chapter 23: Systems Biology: A Four-Step Process 387
Jennifer L. Reed and Bernhard O. Palsson

Chapter 24: Bioinformatics and Systems Biology: Obtaining the Design 401
Principles of Living Systems
Shankar Subramaniam

Chapter 25: Synthetic Biology: Bioengineering at the Genomic Level 427
Natalie Ostroff, Mike Ferry, Scott Cookson, Tracy Johnson and Jeff Hasty

Chapter 26: Network Genomics 453
Trey Ideker

Chapter 27: Genomes, Genomic Technologies and Medicine 473
Xiaohua Huang

SECTION VIII: SOCIO-ECONOMICALASPECTS OF
BIOENGINEERING

Chapter 28: Ethics for Bioengineers 489
Michael Kalichman

Chapter 29: Opportunities and
Challenges in Bioengineering 507
Entrepreneurship
Jen-Shih Lee

Chapter 30: How to Move Medical Devices from Bench to Bedside 521
Paul Citron

Index 533
Springer 國外現貨
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